REAPPRAISAL OF SERUM β2-MICROGLOBULIN AS MARKER OF GFR
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چکیده
منابع مشابه
SERUM CYSTATIN C AS A NEW MARKER OF GLOMERULAR FILTRATION RATE (GFR)
Cystatin C is a 13 KD basic protein that is a member of the cystatin superfamily of cysteine protease inhibitors. The cystatin C gene seems to be a house keeping gene, which is compatible with a stable production rate of cystatin C by most cells. This protein is freely filtered through the glomerulus and almost completely reabsorbed and catabolized by proximal tubular cells. Because of the...
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BACKGROUND/AIMS β2-microglobulin (β2-MG) is freely filtered at the glomerulus and subsequently reabsorbed and catabolized by proximal renal tubular cells. Urinary β2-MG is an early and sensitive biomarker of acute kidney injury; however, its utility as a biomarker of immunoglobulin A nephropathy (IgAN) is unclear. METHODS We included urinary β2-MG levels in the routine laboratory examination ...
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Introduction: Sickle cell nephropathy is a cause of significant morbidity and mortality in patients with sickle cell disease. Traditional creatinine based assay for evaluating renal function has several limitations. Hence, the need for more sensitive markers such as β2 microglobulin (β2M). This study seeks to compare β2M with creatinine as a marker of renal damage in patients with sickle cell d...
متن کاملserum cystatin c as a new marker of glomerular filtration rate (gfr)
cystatin c is a 13 kd basic protein that is a member of the cystatin superfamily of cysteine protease inhibitors. the cystatin c gene seems to be a house keeping gene, which is compatible with a stable production rate of cystatin c by most cells. this protein is freely filtered through the glomerulus and almost completely reabsorbed and catabolized by proximal tubular cells. because of these ch...
متن کاملBeta trace protein as GFR marker in children
Background and Objective: Serum creatinine is the most used endogenous marker of glomerular filtration rate (GFR), but it also has multiple limitations. Therefore, some surrogate GFR markers, such as beta trace protein, have been introduced for GFR estimation. The aim of our study was to estimate GFR by serum beta trace protein using three available equations and compare them to DTPA GFR as the...
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ژورنال
عنوان ژورنال: Renal Failure
سال: 2001
ISSN: 0886-022X,1525-6049
DOI: 10.1081/jdi-100104725